Benzene, 1,3-diiodo-2-methyl-5-nitro-

Base Information

• Chemical Name: Benzene, 1,3-diiodo-2-methyl-5-nitro-
• CAS No.: 10388-20-2
• Molecular Formula: C7H5I2NO2
• Molecular Weight: 388.931
• Mol file: 10388-20-2.mol

Synonyms:

Chemical Property of Benzene, 1,3-diiodo-2-methyl-5-nitro-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1,3-diiodo-2-methyl-5-nitro-

There total 3 articles about Benzene, 1,3-diiodo-2-methyl-5-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-methyl-4-nitrobenzene (99-99-0) → 1,3-diiodo-2-methyl-5-nitrobenzene (10388-20-2)

Guidance literature:

With sodium periodate; sulfuric acid; iodine; at 25 - 30 ℃; for 2h;

DOI:10.1055/s-2006-926374

Reference yield:

4-nitro-toluene-2,6-disulfonyl chloride → 1,3-diiodo-2-methyl-5-nitrobenzene (10388-20-2)

Guidance literature:

With mercury dichloride; sodium sulfite; Behandeln des Reaktionsprodukts mit einer Suspension von Jod in Tetrachlormethan;

DOI:10.1021/ja01616a079

Reference yield:

4-nitro-toluene-2,6-disulfonic acid (874514-00-8) → 1,3-diiodo-2-methyl-5-nitrobenzene (10388-20-2)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅

2: aqueous sodium sulfite solution; mercury (II)-chloride / Behandeln des Reaktionsprodukts mit einer Suspension von Jod in Tetrachlormethan

With phosphorus pentachloride; mercury dichloride; sodium sulfite;

DOI:10.1021/ja01616a079

upstream raw materials:

1-methyl-4-nitrobenzene

4-nitro-toluene-2,6-disulfonic acid

Downstream raw materials:

2,4,6-triiodo-toluene

3.5-Dijodo-4-methylanilin

Refernces

• 1、 Chaikovskii,Filimonov,Skorokhodov,Ogorodnikov. "Superactivity and dual reactivity of the system N-iodosuccinimide-H 2SO4 in the iodination of deactivated arenes". . p. 1278 - 1281. Retrieved 2007.
• 2、 Kraszkiewicz, Lukasz,Sosnowski, Maciej,Skulski, Lech. "Oxidative iodination of deactivated arenes in concentrated sulfuric acid with I2/NaIO4 and KI/NaIO4 iodinating systems". . p. 1195 - 1199. Retrieved 2007/10/03.