(R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester

Base Information

Chemical Name:(R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester
CAS No.:686298-19-1
Molecular Formula:C₂₉H₃₅N₅O₄
Molecular Weight:517.628
Hs Code.:

(R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester

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Chemical Property of (R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester

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Technology Process of (R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester

There total 1 articles about (R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 41864-22-6
1,1'-Carbonyl-di-(1,2,4-triazole)

: 205058-49-7
2,4-dihydro-2-(4-piperidinyl)-5-phenyl-1,2,4-triazol-3(3H)-one

: 686298-14-6
(R)-2-amino-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester

: 686298-19-1
(R)-2-{[4-(5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazol-1-yl)-piperidin-1-carbonyl]-amino}-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester

Guidance literature:: 1,1'-Carbonyl-di-(1,2,4-triazole); (R)-2-amino-3-(5,6,7,8-tetrahydro-naphthalene-2-yl)-propionic acid ethylester; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

2,4-dihydro-2-(4-piperidinyl)-5-phenyl-1,2,4-triazol-3(3H)-one; for 3h; Heating / reflux;