C₁₈H₂₆ClFN₂

Base Information

• Chemical Name: C₁₈H₂₆ClFN₂
• CAS No.: 1384179-46-7
• Molecular Formula: C₁₈H₂₆ClFN₂
• Molecular Weight: 324.869
• Mol file: 1384179-46-7.mol

Synonyms:

Chemical Property of C₁₈H₂₆ClFN₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₆ClFN₂

There total 3 articles about C₁₈H₂₆ClFN₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

C18H24ClFN2O (1384179-43-4) → C18H26ClFN2 (1384179-46-7)

Guidance literature:

With borane-THF; In tetrahydrofuran; for 4h; Reflux;

DOI:10.1016/j.bmcl.2012.05.030

Reference yield:

FECNT (281667-94-5) → C18H26ClFN2 (1384179-46-7)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride; water / 12 h / Reflux

2: oxalyl dichloride / dichloromethane / 4 h / 20 °C

3: dichloromethane / 8 h / 20 °C

4: borane-THF / tetrahydrofuran / 4 h / Reflux

With hydrogenchloride; borane-THF; oxalyl dichloride; water; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.bmcl.2012.05.030

Reference yield:

C16H19ClFNO2 (1384179-37-6) → C18H26ClFN2 (1384179-46-7)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl dichloride / dichloromethane / 4 h / 20 °C

2: dichloromethane / 8 h / 20 °C

3: borane-THF / tetrahydrofuran / 4 h / Reflux

With borane-THF; oxalyl dichloride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.bmcl.2012.05.030

upstream raw materials:

FECNT

C₁₆H₁₉ClFNO₂

C₁₈H₂₄ClFN₂O