Technology Process of C18H20N2O6
There total 10 articles about C18H20N2O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate
2: tetrabutyl ammonium fluoride / tetrahydrofuran
3: pyridine
4: sodium hydroxide / 1,4-dioxane; water
5: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane
With
pyridine; N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water;
1: Vorbruggen reaction;
DOI:10.1016/j.bmcl.2011.11.012
- Guidance literature:
-
Multi-step reaction with 8 steps
2: sodium hydride / N,N-dimethyl-formamide
3: sulfuric acid; acetic acid
4: N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate
5: tetrabutyl ammonium fluoride / tetrahydrofuran
6: pyridine
7: sodium hydroxide / 1,4-dioxane; water
8: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane
With
pyridine; N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate; sulfuric acid; tetrabutyl ammonium fluoride; sodium hydride; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;
1: Grignard reaction / 4: Vorbruggen reaction;
DOI:10.1016/j.bmcl.2011.11.012