C₁₅H₁₉N₃O₄

Base Information

• Chemical Name: C₁₅H₁₉N₃O₄
• CAS No.: 1355242-09-9
• Molecular Formula: C₁₅H₁₉N₃O₄
• Molecular Weight: 305.334
• Mol file: 1355242-09-9.mol

Synonyms:

Chemical Property of C₁₅H₁₉N₃O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₉N₃O₄

There total 9 articles about C₁₅H₁₉N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C36H37N3O4 → C15H19N3O4 (1355242-09-9)

Guidance literature:

With 20% palladium hydroxide on charcoal; ammonium formate; In methanol; for 3h; Reflux;

DOI:10.1021/ja2104679

Reference yield:

3,4,6-tri-O-benzyl-D-galactal (80040-79-5) → C15H19N3O4 (1355242-09-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: hydrogenchloride / tetrahydrofuran; water / 16 h / 20 °C

2.1: pyridinium chlorochromate / dichloromethane / 12 h / 20 °C

3.1: potassium hexamethylsilazane / toluene / 0.25 h / -78 °C

3.2: 0.08 h / -78 °C

4.1: diethyl ether; toluene / 1 h / -78 °C

5.1: triethylsilane / acetonitrile / 0.08 h / -40 °C

5.2: -40 - 20 °C

6.1: copper(II) sulfate; sodium L-ascorbate / methanol; water

7.1: 20% palladium hydroxide on charcoal; ammonium formate / methanol / 3 h / Reflux

With hydrogenchloride; triethylsilane; 20% palladium hydroxide on charcoal; ammonium formate; potassium hexamethylsilazane; copper(II) sulfate; sodium L-ascorbate; pyridinium chlorochromate; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; toluene; acetonitrile;

DOI:10.1021/ja2104679

Reference yield:

(2R,3R,4R)-3,4-bis-benzyloxy-2-benzyloxymethyltetrahydropyran-5-one (72605-77-7,79999-46-5) → C15H19N3O4 (1355242-09-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: potassium hexamethylsilazane / toluene / 0.25 h / -78 °C

1.2: 0.08 h / -78 °C

2.1: diethyl ether; toluene / 1 h / -78 °C

3.1: triethylsilane / acetonitrile / 0.08 h / -40 °C

3.2: -40 - 20 °C

4.1: copper(II) sulfate; sodium L-ascorbate / methanol; water

5.1: 20% palladium hydroxide on charcoal; ammonium formate / methanol / 3 h / Reflux

With triethylsilane; 20% palladium hydroxide on charcoal; ammonium formate; potassium hexamethylsilazane; copper(II) sulfate; sodium L-ascorbate; In methanol; diethyl ether; water; toluene; acetonitrile;

DOI:10.1021/ja2104679

upstream raw materials:

3,4,6-tri-O-benzyl-D-galactal

(2R,3R,4R)-3,4-bis-benzyloxy-2-benzyloxymethyltetrahydropyran-5-one

(3R,4R,5R,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one

D-galactal