methyl 3-deuteroxybenzoate

Base Information

• Chemical Name: methyl 3-deuteroxybenzoate
• CAS No.: 65750-33-6
• Molecular Formula: C₈H₈O₃
• Molecular Weight: 153.142
• Mol file: 65750-33-6.mol

Synonyms:

Chemical Property of methyl 3-deuteroxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-deuteroxybenzoate

There total 2 articles about methyl 3-deuteroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-(2S,3R)-methyl 2,3-isopropylidenedioxycyclohexa-4,6-dienecarboxylate (1264530-23-5) → C8H8(2)H2O4 + methyl 3-deuteroxybenzoate (65750-33-6)

Guidance literature:

With d⁽⁴⁾-methanol; iodine; at 50 ℃; for 1.58333h; Inert atmosphere;

DOI:10.1039/c0cc01169j

Reference yield:

(3aS,7aR)-methyl 2,2-dimethyl-3a,7a-dihydrobenzo[d][1,3]dioxole-3a-carboxylate (172877-75-7) → C8H8(2)H2O4 + methyl 3-deuteroxybenzoate (65750-33-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diiron nonacarbonyl / tetrahydrofuran / 384 h / 20 °C / Inert atmosphere

1.2: 5 h / 20 °C / Inert atmosphere

2.1: d⁽⁴⁾-methanol; iodine / 1.58 h / 50 °C / Inert atmosphere

With diiron nonacarbonyl; d⁽⁴⁾-methanol; iodine; In tetrahydrofuran;

DOI:10.1039/c0cc01169j

upstream raw materials:

(-)-(2S,3R)-methyl 2,3-isopropylidenedioxycyclohexa-4,6-dienecarboxylate

(3aS,7aR)-methyl 2,2-dimethyl-3a,7a-dihydrobenzo[d][1,3]dioxole-3a-carboxylate