5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

Base Information

Chemical Name:5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide
CAS No.:1252801-15-2
Molecular Formula:C₄₄H₄₈N₆O₄
Molecular Weight:724.903
Hs Code.:

5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

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Technology Process of 5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

There total 6 articles about 5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₇₇H₇₃F₁₇N₁₀O₈

: 1252801-15-2
5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 25 ℃; for 3.5h;
DOI:10.1021/co2002153

Reference yield:

: 5521-55-1
2-methylpyrazin-5-carboxylic acid

: 1252973-65-1
C₃₈H₄₄N₄O₃

: 1252801-15-2
5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

Guidance literature:: With 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; at 25 ℃; for 24h;
DOI:10.1016/j.bmcl.2010.09.032

Reference yield:

: 5521-55-1
2-methylpyrazin-5-carboxylic acid

: 1252801-37-8
C₃₈H₄₄N₄O₃*ClH

: 1252801-15-2
5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide

Guidance literature:: With 2,4,6-trimethyl-pyridine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 25 ℃; for 3h;
DOI:10.1042/BJ20100383