tert-butyl (7S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-8-oxo-8-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]octanoate

Base Information

• Chemical Name: tert-butyl (7S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-8-oxo-8-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]octanoate
• CAS No.: 1252036-06-8
• Molecular Formula: C₄₀H₄₆N₄O₅
• Molecular Weight: 662.829
• Mol file: 1252036-06-8.mol

Synonyms:

Chemical Property of tert-butyl (7S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-8-oxo-8-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]octanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (7S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-8-oxo-8-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]octanoate

There total 1 articles about tert-butyl (7S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-8-oxo-8-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]octanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(9H-fluoren-9-ylmethoxycarbonylamino)-octanedioic acid 8-tert-butyl ester (276869-41-1) + (2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboxylate hydrochloride → tert-butyl (7S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-8-oxo-8-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]octanoate (1252036-06-8)

Guidance literature:

With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/jm101013m

upstream raw materials:

2-(9H-fluoren-9-ylmethoxycarbonylamino)-octanedioic acid 8-tert-butyl ester