8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-ol

Base Information

Chemical Name:8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-ol
CAS No.:13459-64-8
Molecular Formula:C₁₄H₁₁ClOS
Molecular Weight:262.76
Hs Code.:
DSSTox Substance ID:DTXSID201245300

Synonyms:8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-ol;3-Chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-ol;DTXSID201245300;AKOS005064165;13459-64-8;AE-641/00686005

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-ol

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:262.0219138
Heavy Atom Count:17
Complexity:273

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C2=C(C=CC(=C2)Cl)SC3=CC=CC=C31)O

Technology Process of 8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-ol

There total 1 articles about 8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13459-64-8
8-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-ol

Guidance literature:: Aus entspr. Amino-thiepin X -> Diazotierung, CH3COONa*3H2O, CuSO4*5H2O u. Na2CO3;
DOI:10.1135/cccc19780471

Reference yield:

: 13459-64-8
8-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-ol

: 13242-44-9
2-(N,N-dimethylamino)ethylthiol hydrochloride

: 72291-43-1
[2-(8-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-ylsulfanyl)-ethyl]-dimethyl-amine

Guidance literature:: With boron trifluoride diethyl etherate; In acetic acid; at 20 ℃; for 72h;
DOI:10.1021/jm00352a010

Reference yield:

: 13459-64-8
8-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-ol

: 93665-48-6
1-<2-(2-chloro-10,11-dihydrodibenzothiepin-11-yloxy)ethyl>-4-methylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: BF₃*Et₂O / benzene / 0.75 h / Ambient temperature

2: 93 percent / 1.) 3 h, 100 deg C; 2.) CHCl₃, 2 h, reflux

With boron trifluoride diethyl etherate; In benzene;
DOI:10.1135/cccc19841810