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C19H27NO4

Base Information
  • Chemical Name:C19H27NO4
  • CAS No.:1301726-02-2
  • Molecular Formula:C19H27NO4
  • Molecular Weight:333.428
  • Hs Code.:
C<sub>19</sub>H<sub>27</sub>NO<sub>4</sub>

Synonyms:

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Chemical Property of C19H27NO4
Chemical Property:
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Technology Process of C19H27NO4

There total 9 articles about C19H27NO4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 9 steps
1.1: potassium osmate(VI) dihydrate; methanesulfonamide; water; potassium carbonate; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; potassium hexacyanoferrate(III) / tert-butyl alcohol / 22 h / 0 - 10 °C
2.1: lithium borohydride; water / tetrahydrofuran
3.1: sodium hydride; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole / tetrahydrofuran / 0 °C
4.1: tetrahydrofuran / 0 - 20 °C
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran
6.1: camphor-10-sulfonic acid / dichloromethane / 20 °C
7.1: diphenyl phosphoryl azide; triphenylphosphine
7.2: 20 °C
8.1: water; triphenylphosphine / tetrahydrofuran
9.1: pyridine
With pyridine; potassium osmate(VI) dihydrate; lithium borohydride; methanesulfonamide; diphenyl phosphoryl azide; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; water; sodium hydride; potassium carbonate; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; triphenylphosphine; potassium hexacyanoferrate(III); 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole; In tetrahydrofuran; dichloromethane; tert-butyl alcohol; 1.1: Sharpless dihydroxylation / 3.1: Fraser-Reid epoxidation;
DOI:10.1016/j.tetlet.2010.11.013
Guidance literature:
Multi-step reaction with 8 steps
1.1: lithium borohydride; water / tetrahydrofuran
2.1: sodium hydride; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole / tetrahydrofuran / 0 °C
3.1: tetrahydrofuran / 0 - 20 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran
5.1: camphor-10-sulfonic acid / dichloromethane / 20 °C
6.1: diphenyl phosphoryl azide; triphenylphosphine
6.2: 20 °C
7.1: water; triphenylphosphine / tetrahydrofuran
8.1: pyridine
With pyridine; lithium borohydride; diphenyl phosphoryl azide; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; water; sodium hydride; triphenylphosphine; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole; In tetrahydrofuran; dichloromethane; 2.1: Fraser-Reid epoxidation;
DOI:10.1016/j.tetlet.2010.11.013
Guidance literature:
Multi-step reaction with 3 steps
1.1: diphenyl phosphoryl azide; triphenylphosphine
1.2: 20 °C
2.1: water; triphenylphosphine / tetrahydrofuran
3.1: pyridine
With pyridine; diphenyl phosphoryl azide; water; triphenylphosphine; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2010.11.013
upstream raw materials:

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