4-Benzoyl-3-methylphenol

Base Information

• Chemical Name: 4-Benzoyl-3-methylphenol
• CAS No.: 10425-07-7
• Molecular Formula: C14H12O2
• Molecular Weight: 212.248
• DSSTox Substance ID: DTXSID101270831
• Nikkaji Number: J406.619G
• Mol file: 10425-07-7.mol

Synonyms:10425-07-7;(4-Hydroxy-2-methylphenyl)(phenyl)methanone;4-Benzoyl-3-methylphenol;SCHEMBL9857539;DTXSID101270831;AKOS019824459;(4-Hydroxy-2-methylphenyl)phenylmethanone;EN300-1276490

Chemical Property of 4-Benzoyl-3-methylphenol

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 212.083729621
• Heavy Atom Count: 16
• Complexity: 243

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)O)C(=O)C2=CC=CC=C2

Technology Process of 4-Benzoyl-3-methylphenol

There total 23 articles about 4-Benzoyl-3-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

3-methylphenyl benzoate (614-32-4) → 2-hydroxy-4-methylbenzophenone (3098-18-8) + 4-hydroxy-2-methylbenzophenone (10425-07-7)

Guidance literature:

With phosphorus pentoxide; silica gel; for 0.0833333h; microwave irradiation;

Reference yield: 60.0%

3-methyl-phenol (108-39-4) + benzoic acid (65-85-0,8013-63-6) → 4-hydroxy-2-methylbenzophenone (10425-07-7)

Guidance literature:

With polyphosphoric acid; for 0.0666667h; Microwave irradiation;

Reference yield: 55.0%

3-methyl-phenol (108-39-4) + benzoic acid (65-85-0,8013-63-6) → 2-hydroxy-4-methylbenzophenone (3098-18-8) + 4-hydroxy-2-methylbenzophenone (10425-07-7)

Guidance literature:

With phosphorus pentoxide; silica gel; for 0.0833333h; microwave irradiation;

upstream raw materials:

3-methylphenyl benzoate

1-(4-methoxy-2-methylphenyl)phenylmethanone

4-hydroxy-5-isopropyl-2-methyl-benzophenone

benzoyl chloride

Downstream raw materials:

4-hydroxy-2-methylbenzoic acid

1-(4-methoxy-2-methylphenyl)phenylmethanone

3-methylphenyl benzoate

2-hydroxy-4-methylbenzophenone