2-Formyl-1H-indole-6-carbonitrile

Base Information

Chemical Name:2-Formyl-1H-indole-6-carbonitrile
CAS No.:104291-63-6
Molecular Formula:C₁₀H₆N₂O
Molecular Weight:170.17
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00544010
Wikidata:Q82420983
Mol file:104291-63-6.mol

Synonyms:2-Formyl-1H-indole-6-carbonitrile;104291-63-6;DTXSID00544010;MFCD12924835;AKOS016007445;DS-17344;CS-0043777;N13179;A896253

Suppliers and Price of 2-Formyl-1H-indole-6-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Formyl-1H-indole-6-carbonitrile 96%
1g
$ 409.00

Chemenu
2-formyl-1H-indole-6-carbonitrile 95%+
1g
$ 386.00

American Custom Chemicals Corporation
2-FORMYL-1H-INDOLE-6-CARBONITRILE 95.00%
5MG
$ 501.04

Alichem
2-Formyl-1H-indole-6-carbonitrile
1g
$ 404.74

AK Scientific
2-Formyl-1H-indole-6-carbonitrile
5g
$ 2121.00

AK Scientific
2-Formyl-1H-indole-6-carbonitrile
1g
$ 608.00

AccelPharmtech
2-formyl-1H-Indole-6-carbonitrile 97.00%
25G
$ 7320.00

AccelPharmtech
2-formyl-1H-Indole-6-carbonitrile 97.00%
1G
$ 2280.00

aablocks
2-Formyl-1h-indole-6-carbonitrile 96%
1g
$ 435.00

aablocks
2-Formyl-1h-indole-6-carbonitrile 96%
250mg
$ 198.00

Total 15 raw suppliers

Chemical Property of 2-Formyl-1H-indole-6-carbonitrile

Chemical Property:

Boiling Point:429.6±25.0 °C(Predicted)
PKA:13.22±0.30(Predicted)
PSA：56.65000
Density:1.33±0.1 g/cm3(Predicted)
LogP:1.85208
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:170.048012819
Heavy Atom Count:13
Complexity:255

Purity/Quality:

97% ^*data from raw suppliers

2-Formyl-1H-indole-6-carbonitrile 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1C#N)NC(=C2)C=O

Technology Process of 2-Formyl-1H-indole-6-carbonitrile

There total 4 articles about 2-Formyl-1H-indole-6-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 104291-65-8
2-(Hydroxymethyl)indol-6-carbonitril

: 104291-63-6
2-formyl-1H-indole-6-carbonitrile

Guidance literature:: With Mangandioxid; In acetone; for 2h; Ambient temperature;

Reference yield:

: 104291-81-8
ethyl 6-cyano-1H-indole-2-carboxylate

: 104291-63-6
2-formyl-1H-indole-6-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent

2: 80 percent / Mangandioxid / acetone / 2 h / Ambient temperature

With Mangandioxid; In acetone;

Reference yield:

: 939-79-7
4-cyano-2-nitrotoluene

: 104291-63-6
2-formyl-1H-indole-6-carbonitrile

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium / ethanol / 16 h / 20 °C

2.1: zinc / water; acetic acid / 0.42 h

3.1: lithium borohydride / tetrahydrofuran / 16 h / Reflux

4.1: manganese(IV) oxide / acetone / 16 h / 20 °C

4.2: 24 h / 20 °C

With manganese(IV) oxide; lithium borohydride; sodium; zinc; In tetrahydrofuran; ethanol; water; acetic acid; acetone;
DOI:10.1016/j.bmc.2013.10.014