N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide

Base Information

• Chemical Name: N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide
• CAS No.: 1160212-28-1
• Molecular Formula: C₂₀H₁₈N₂O₇S
• Molecular Weight: 430.438
• Mol file: 1160212-28-1.mol

Synonyms:

Chemical Property of N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide

There total 5 articles about N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C26H24N2O10S → N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide (1160212-28-1)

Guidance literature:

With hydrogenchloride; water; In tetrahydrofuran; methanol; at 60 ℃; for 1h;

DOI:10.1016/j.bmcl.2009.06.100

Reference yield:

3,4,5-triacetoxybenzoic acid (6635-24-1) → N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide (1160212-28-1)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / 5 h / 80 °C

2: pyridine / acetone / 20 h / 0 - 20 °C

3: hydrogenchloride / water; methanol; tetrahydrofuran / 1 h / 60 °C

With pyridine; hydrogenchloride; thionyl chloride; In tetrahydrofuran; methanol; water; acetone;

DOI:10.3109/14756366.2011.604851

Reference yield:

p-acetylaminobenzenesulfonyl chloride (121-60-8) → N-(4-(4-methoxyphenylsulfamoyl)phenyl)galloylamide (1160212-28-1)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / 4 h / 0 - 20 °C

2: sodium hydroxide / methanol / 3 h / 70 °C

3: pyridine / acetone / 20 h / 0 - 20 °C

4: hydrogenchloride / water; methanol; tetrahydrofuran / 1 h / 60 °C

With pyridine; hydrogenchloride; sodium hydroxide; In tetrahydrofuran; methanol; water; acetone;

DOI:10.3109/14756366.2011.604851

upstream raw materials:

3,4,5-trihydroxybenzoic acid

3,4,5-triacetoxybenzoic acid

3,4,5-triacetoxybenzoyl chloride

N-(4-methoxyphenyl)-4-aminobenzenesulfonamide

Refernces

• 1、 Wang, Peng,Liu, Chuan,Sanches, Tino,Zhong, Yuan,Liu, Bo,Xiong, Junlong,Neamati, Nouri,Zhao, Guisen. "Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester". supporting information; experimental part. p. 4574 - 4578. Retrieved 2010/04/24.