Technology Process of 1,2-di-O-acetyl-3-O-benzyl-5-deoxy-3-C-isopropyl-β-D-lyxofuranose
There total 5 articles about 1,2-di-O-acetyl-3-O-benzyl-5-deoxy-3-C-isopropyl-β-D-lyxofuranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 52 percent / diethyl ether; diethyl ether / 1.) -78 deg C -> r.t.; 2.) r.t. overnight
2: 1.) 50 percent NaH / 1.) DMF, r.t., 30 min; 2.) r.t., overnight
3: 1.) 70 percent acetic acid - 6 N hydrochloric acid / 1.) r.t., 2 h; 2.) pyridine, r.t., overnight
With
hydrogenchloride; sodium hydride; acetic acid;
In
diethyl ether;
DOI:10.1246/bcsj.60.4107
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) 50 percent NaH / 1.) DMF, r.t., 30 min; 2.) r.t., overnight
2: 1.) 70 percent acetic acid - 6 N hydrochloric acid / 1.) r.t., 2 h; 2.) pyridine, r.t., overnight
With
hydrogenchloride; sodium hydride; acetic acid;
DOI:10.1246/bcsj.60.4107
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 94 percent / NaH / dimethylformamide / 0 - 25 °C
2: 1.) acetic acid, hydrochloric acid, 2.) pyridine
With
pyridine; hydrogenchloride; sodium hydride; acetic acid;
In
N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)94265-5
