B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone

Base Information

• Chemical Name: B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone
• CAS No.: 107895-17-0
• Molecular Formula: C₃₃H₄₆N₄O₄
• Molecular Weight: 562.753
• Mol file: 107895-17-0.mol

Synonyms:

Chemical Property of B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone

There total 7 articles about B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

B-nor-cholesta-3,5-diene-6-carbaldehyde (92944-13-3) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone (107895-17-0)

Guidance literature:

With sulfuric acid; In methanol; diethyl ether; for 0.75h;

Reference yield:

Cholesteryl acetate (604-35-3) → B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone (107895-17-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 546 mg / ozone / CH₂Cl₂; methanol / 1.5 h / -40 - -35 °C

2: 3.35 g / p-toluenesulfonic acid monohydrate / methanol / 4 h / -23 °C

3: 74 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / hexane / 19 h / Ambient temperature

4: 83 percent / 7percent oxalic acid, SiO₂ / CH₂Cl₂; H₂O / 2 h / Ambient temperature

5: 77 percent / Al₂O₃ / benzene / 7 h / Ambient temperature

6: 44 percent / concentrated sulfuric acid / diethyl ether; methanol / 0.75 h

With aluminum oxide; sulfuric acid; oxalic acid; silica gel; toluene-4-sulfonic acid; ozone; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; diethyl ether; hexane; dichloromethane; water; benzene;

Reference yield:

3β-acetoxy-5-oxo-5,6-seco-cholestan-6-al (19289-53-3) → B-nor-cholesta-3,5-diene-6-(2,4-dinitrophenyl)hydrazone (107895-17-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 3.35 g / p-toluenesulfonic acid monohydrate / methanol / 4 h / -23 °C

2: 74 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / hexane / 19 h / Ambient temperature

3: 83 percent / 7percent oxalic acid, SiO₂ / CH₂Cl₂; H₂O / 2 h / Ambient temperature

4: 77 percent / Al₂O₃ / benzene / 7 h / Ambient temperature

5: 44 percent / concentrated sulfuric acid / diethyl ether; methanol / 0.75 h

With aluminum oxide; sulfuric acid; oxalic acid; silica gel; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; diethyl ether; hexane; dichloromethane; water; benzene;

upstream raw materials:

B-nor-cholesta-3,5-diene-6-carbaldehyde

(2,4-dinitro-phenyl)-hydrazine

Cholesteryl acetate

3β-acetoxy-5-oxo-5,6-seco-cholestan-6-al