cis-(glyglyOEt)2PtCl₂

Base Information

• Chemical Name: cis-(glyglyOEt)2PtCl₂
• CAS No.: 39680-31-4
• Molecular Formula: C₁₂H₂₄Cl₂N₄O₆Pt
• Molecular Weight: 586.332
• Mol file: 39680-31-4.mol

Synonyms:

Chemical Property of cis-(glyglyOEt)2PtCl₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of cis-(glyglyOEt)2PtCl₂

There total 3 articles about cis-(glyglyOEt)2PtCl₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

potassium tetrachloroplatinate + glycyl glycine ethyl ester hydrochloride (2087-41-4) → cis-(glyglyOEt)2PtCl2 (39680-31-4,60426-60-0)

Guidance literature:

With KOH; In water; by dropping aq. KOH to aq. soln. of educts; stirring for 1 h; filtering, washing with water and ether, drying in high vac.; elem. anal.;

DOI:10.1002/cber.19821150621

Reference yield: 46.0%

cis-[Pt(II)(glycine)2Cl2] (17567-45-2) + glycine ethyl ester hydrochloride (623-33-6) → cis-(glyglyOEt)2PtCl2 (39680-31-4,60426-60-0)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In water; byproducts: EtNHC(O)NH(CH2)3NMe2; Pt complex, amino acid ester and carbodiimide (molar ratio 1:3:3) were mixed in H2O and the base added dropwise at room temp. within 3-4 h; the mixt. was stirred for 1 d;; the ppt., forming a creamy suspension, was separacted bx suction-filtration, washed with H2O and ether, and dried in vac.; elem. anal.;

Reference yield: 34.0%

trans-[Pt(glycine)2Cl2] (17567-40-7) + glycine ethyl ester hydrochloride (623-33-6) → PtCl2(NH2CH2CONHCH2COOC2H5)2 (60426-60-0,39680-31-4)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In water; byproducts: EtNHC(O)NH(CH2)3NMe2; Pt complex, amino acid ester and carbodiimide (molar ratio 1:3:3) were mixed in H2O and the base added dropwise at room temp. within 3-4 h; the mixt. was stirred for 1 d;; the ppt., forming a creamy suspension, was separacted bx suction-filtration, washed with H2O and ether, and dried in vac.; elem. anal.;

upstream raw materials:

glycyl glycine ethyl ester hydrochloride

cis-[Pt(II)(glycine)2Cl₂]

glycine ethyl ester hydrochloride

trans-[Pt(glycine)2Cl₂]