C₃₇H₅₅NO₅Si

Base Information

• Chemical Name: C₃₇H₅₅NO₅Si
• CAS No.: 129056-39-9
• Molecular Formula: C₃₇H₅₅NO₅Si
• Molecular Weight: 621.933
• Mol file: 129056-39-9.mol

Synonyms:

Chemical Property of C₃₇H₅₅NO₅Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₅₅NO₅Si

There total 14 articles about C₃₇H₅₅NO₅Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(7S,13E,16S,17R,18R,19E)-7-tert-Butyldimethylsilyloxy-17,18-isopropylidenedioxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,21-dione (129056-41-3) → (7S,13E,16S,17R,18R,19E,21R)-7-tert-Butyldimethylsilyloxy-21-hydroxy-17,18-isopropylidenedioxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1-one (129056-42-4) + C37H55NO5Si (129056-39-9)

Guidance literature:

With sodium tetrahydroborate; cerium(III) chloride;

DOI:10.1039/c39900000464

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) → C37H55NO5Si (129056-39-9)

Guidance literature:

Multi-step reaction with 8 steps

1: 90 percent / 2,6-lutidine

2: 75 percent / SOCl₂, triethylamine

3: 75 percent / OsO₄

4: 100 percent / toluene p-sulphonic acid / CHCl₃

5: 70 percent / lithium di-isopropylamide (LDA) / -35 °C

6: 85 percent / KOH / methanol

7: 67 percent / H₂O₂ / H₂O; pyridine

8: NaBH₄, CeCl₃

With 2,6-dimethylpyridine; potassium hydroxide; sodium tetrahydroborate; osmium(VIII) oxide; thionyl chloride; cerium(III) chloride; dihydrogen peroxide; toluene-4-sulfonic acid; triethylamine; lithium diisopropyl amide; In pyridine; methanol; chloroform; water;

DOI:10.1039/c39900000464

Reference yield:

(5R)-1-benzoyl-5-benzylpyrrolidin-2-one (94063-58-8) → C37H55NO5Si (129056-39-9)

Guidance literature:

Multi-step reaction with 12 steps

2: 1.) LiN(SiMe₃)2, PhSeCl, 2.) m-chloroperoxybenzoic acid, H₂O₂ / 2.) from -50 deg C to 0 deg C

3: toluene / 80 °C

4: 55 percent / OsO₄

5: 90 percent / 2,6-lutidine

6: 75 percent / SOCl₂, triethylamine

7: 75 percent / OsO₄

8: 100 percent / toluene p-sulphonic acid / CHCl₃

9: 70 percent / lithium di-isopropylamide (LDA) / -35 °C

10: 85 percent / KOH / methanol

11: 67 percent / H₂O₂ / H₂O; pyridine

12: NaBH₄, CeCl₃

With 2,6-dimethylpyridine; potassium hydroxide; sodium tetrahydroborate; osmium(VIII) oxide; thionyl chloride; Phenylselenyl chloride; cerium(III) chloride; dihydrogen peroxide; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; lithium diisopropyl amide; In pyridine; methanol; chloroform; water; toluene;

DOI:10.1039/c39900000464

upstream raw materials:

(7S,13E,16S,17R,18R,19E)-7-tert-Butyldimethylsilyloxy-17,18-isopropylidenedioxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6⁽¹²⁾,13,19-triene-1,21-dione

t-butyldimethylsiyl triflate

(5R)-1-benzoyl-5-benzylpyrrolidin-2-one

1-[(4E,6S,8E,10E,12E)-4,6,12-Trimethyltetradecatetra-4,8,10,12-enoyl]imidazole