Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate

Base Information

• Chemical Name: Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate
• CAS No.: 135138-03-3
• Molecular Formula: C₃₇H₅₆O₅Si₂
• Molecular Weight: 637.02
• Mol file: 135138-03-3.mol

Synonyms:

Chemical Property of Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate

There total 3 articles about Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-hydroxymethylcyclopentyl>hept-5-enoate (135138-02-2) → Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate (135138-03-3)

Guidance literature:

DOI:10.1248/cpb.39.309

Reference yield:

Methyl (Z)-<(1R,2S,3R)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-methylenecyclopentyl>hept-5-enoate (135138-01-1) → Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate (135138-03-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent

2: 100 percent

DOI:10.1248/cpb.39.309

Reference yield:

methyl (Z)-7-<(1R,2S,3R)-2-tert-butyldimethylsilyloxymethyl-5-methylene-3-tetrahydropyranyloxycyclopentyl>hept-5-enoate (90934-01-3) → Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-formylcyclopentyl>hept-5-enoate (135138-03-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent

2: 78 percent

3: 100 percent

DOI:10.1248/cpb.39.309

upstream raw materials:

Methyl (Z)-<(1R,2S,3R,5S)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-hydroxymethylcyclopentyl>hept-5-enoate

methyl (Z)-7-<(1R,2S,3R)-2-tert-butyldimethylsilyloxymethyl-5-methylene-3-tetrahydropyranyloxycyclopentyl>hept-5-enoate

Methyl (Z)-<(1R,2S,3R)-2-tert-Butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-methylenecyclopentyl>hept-5-enoate

Downstream raw materials:

Methyl (1R,5S,6S,7R)-6-tert-Butyldimethylsilyloxymethyl-7-tert-butyldiphenylsilyloxybicyclo<3.3.0>octe-2-ene-3-γ-pentenoate

(E)-5-[(1S,2R,3aS,4S,5R,6aS)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-(tert-butyl-diphenyl-silanyloxy)-1-hydroxy-octahydro-pentalen-2-yl]-pent-4-enoic acid methyl ester

Methyl (1S,5S,6S,7R)-6-tert-Butyldimethylsilyloxymethyl-7-tert-butyldiphenylsilyloxybicyclo<3.3.0>octane-E-Δ^3,δ-pentanoate

(E)-5-[(1S,2R,3aS,4S,5R,6aS)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-(tert-butyl-diphenyl-silanyloxy)-1-methanesulfonyloxy-octahydro-pentalen-2-yl]-pent-4-enoic acid methyl ester