Fucα1-2Galβ1-3GalNAcβ-OCH₂CH₂CH₂NH₂

Base Information

• Chemical Name: Fucα1-2Galβ1-3GalNAcβ-OCH₂CH₂CH₂NH₂
• CAS No.: 1016164-81-0
• Molecular Formula: C₂₃H₄₂N₂O₁₅
• Molecular Weight: 586.591
• Mol file: 1016164-81-0.mol

Synonyms:

Chemical Property of Fucα1-2Galβ1-3GalNAcβ-OCH₂CH₂CH₂NH₂

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Fucα1-2Galβ1-3GalNAcβ-OCH₂CH₂CH₂NH₂

There total 9 articles about Fucα1-2Galβ1-3GalNAcβ-OCH₂CH₂CH₂NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4-tri-O-acetyl-6-O-benzyl-α-D-galactopyranosyl bromide (290330-34-6) → Fucα1-2Galβ1-3GalNAcβ-OCH2CH2CH2NH2 (1016164-81-0)

Guidance literature:

Multi-step reaction with 9 steps

1: silver trifluoromethanesulfonate; tetramethylurea / dichloromethane / 20 °C / Molecular sieve

2: sodium methylate / methanol / 1 h

3: toluene-4-sulfonic acid / methanol / 1 h

4: silver trifluoromethanesulfonate; tetramethylurea / dichloromethane / 16 h / 20 °C / Molecular sieve

5: acetic acid; water / 2 h / 70 °C

6: hydrogen; palladium on activated charcoal / methanol

7: pyridine / 24 h

8: sodium methylate / methanol / 1 h

9: water; sodium hydroxide / 16 h

With pyridine; palladium on activated charcoal; water; hydrogen; sodium methylate; silver trifluoromethanesulfonate; toluene-4-sulfonic acid; acetic acid; tetramethylurea; sodium hydroxide; In methanol; dichloromethane;

DOI:10.1016/j.mencom.2018.07.027

Reference yield:

C31H37F3N4O11 → Fucα1-2Galβ1-3GalNAcβ-OCH2CH2CH2NH2 (1016164-81-0)

Guidance literature:

Multi-step reaction with 7 steps

1: toluene-4-sulfonic acid / methanol / 1 h

2: silver trifluoromethanesulfonate; tetramethylurea / dichloromethane / 16 h / 20 °C / Molecular sieve

3: acetic acid; water / 2 h / 70 °C

4: hydrogen; palladium on activated charcoal / methanol

5: pyridine / 24 h

6: sodium methylate / methanol / 1 h

7: water; sodium hydroxide / 16 h

With pyridine; palladium on activated charcoal; water; hydrogen; sodium methylate; silver trifluoromethanesulfonate; toluene-4-sulfonic acid; acetic acid; tetramethylurea; sodium hydroxide; In methanol; dichloromethane;

DOI:10.1016/j.mencom.2018.07.027

Reference yield:

C51H61F3N4O15 → Fucα1-2Galβ1-3GalNAcβ-OCH2CH2CH2NH2 (1016164-81-0)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogen; palladium on activated charcoal / methanol

2: pyridine / 24 h

3: sodium methylate / methanol / 1 h

4: water; sodium hydroxide / 16 h

With pyridine; palladium on activated charcoal; water; hydrogen; sodium methylate; sodium hydroxide; In methanol;

DOI:10.1016/j.mencom.2018.07.027

upstream raw materials:

2,3,4-tri-O-acetyl-6-O-benzyl-α-D-galactopyranosyl bromide

3-trifluoroacetamidopropyl 2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside