N-Allyl-p-hydroxybenzamide

Base Information

• Chemical Name: N-Allyl-p-hydroxybenzamide
• CAS No.: 90921-72-5
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.203
• DSSTox Substance ID: DTXSID001296076
• Nikkaji Number: J1.398.047K
• Mol file: 90921-72-5.mol

Synonyms:N-Allyl-p-hydroxybenzamide;N-Allyl-4-hydroxybenzamide;N-Allyl-4-hydroxybenzamide #;SCHEMBL5884635;DTXSID001296076;4-Hydroxy-N-2-propen-1-ylbenzamide;AKOS000207206;90921-72-5

Chemical Property of N-Allyl-p-hydroxybenzamide

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 177.078978594
• Heavy Atom Count: 13
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CCNC(=O)C1=CC=C(C=C1)O

Technology Process of N-Allyl-p-hydroxybenzamide

There total 4 articles about N-Allyl-p-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) + 1-amino-2-propene (107-11-9,30551-89-4) → 4-hydroxy-benzoic acid allylamide (90921-72-5)

Guidance literature:

DOI:10.1021/ja01542a036

Reference yield:

1-amino-2-propene (107-11-9,30551-89-4) + Sodium; 4-allyloxycarbonyl-phenolate → 4-hydroxy-benzoic acid allylamide (90921-72-5)

Guidance literature:

Multistep reaction;

DOI:10.1016/S0040-4039(98)01473-7

Reference yield:

N-allyl isothiocyanate (57-06-7,58391-87-0) + 4-hydroxy-benzoic acid (99-96-7) → 4-hydroxy-benzoic acid allylamide (90921-72-5)

Guidance literature:

upstream raw materials:

methyl 4-hydroxylbenzoate

1-amino-2-propene

N-allyl isothiocyanate

4-hydroxy-benzoic acid

Downstream raw materials:

(4-allylcarbamoyl-phenoxy)-acetic acid