(+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol

Base Information

• Chemical Name: (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol
• CAS No.: 124320-15-6
• Molecular Formula: C₂₈H₃₆O₅S
• Molecular Weight: 484.657
• Mol file: 124320-15-6.mol

Synonyms:

Chemical Property of (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol

There total 3 articles about (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-2c-methallyl-7-methoxy-(4ar,10at)-3,4,4a,9,10,10a-hexahydro-2H-phenanthren-1-one (109689-57-8) → (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol (124320-15-6)

Guidance literature:

Multi-step reaction with 3 steps

2: LiAlH₄; diethyl ether

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01580a053

Reference yield:

(+/-)-(1-hydroxy-2c-methallyl-7-methoxy-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1t]phenanthryl)-acetic acid ethyl ester (113252-38-3) → (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol (124320-15-6)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄; diethyl ether

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01580a053

Reference yield:

(+/-)-1-(2-hydroxy-ethyl)-2c-methallyl-7-methoxy-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol (110748-22-6) + p-toluenesulfonyl chloride (98-59-9) → (+/-)-2c-methallyl-7-methoxy-1-[2-(toluene-4-sulfonyloxy)-ethyl]-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol (124320-15-6)

Guidance literature:

DOI:10.1021/ja01580a053

upstream raw materials:

(+/-)-1-(2-hydroxy-ethyl)-2c-methallyl-7-methoxy-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1c]phenanthrol

p-toluenesulfonyl chloride

(+/-)-2c-methallyl-7-methoxy-(4ar,10at)-3,4,4a,9,10,10a-hexahydro-2H-phenanthren-1-one

(+/-)-(1-hydroxy-2c-methallyl-7-methoxy-(4ar,10at)-1,2,3,4,4a,9,10,10a-octahydro-[1t]phenanthryl)-acetic acid ethyl ester