Benzene, 2-azido-4-chloro-1-nitro-

Base Information

• Chemical Name: Benzene, 2-azido-4-chloro-1-nitro-
• CAS No.: 104503-85-7
• Molecular Formula: C6H3ClN4O2
• Molecular Weight: 198.568
• Mol file: 104503-85-7.mol

Synonyms:

Chemical Property of Benzene, 2-azido-4-chloro-1-nitro-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 2-azido-4-chloro-1-nitro-

There total 3 articles about Benzene, 2-azido-4-chloro-1-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-nitroaniline (1635-61-6) → 2-azido-4-chloro-1-nitrobenzene (104503-85-7)

Guidance literature:

With hydrogenchloride; sodium azide; sodium acetate; sodium nitrite; Yield given. Multistep reaction; 1.) from 2 to 4 deg C, 15 min, 2.) 0 deg C, 30 min;

DOI:10.1071/CH9860089

Reference yield:

4-chloro-2-fluoro-nitrobenzene (700-37-8) → 2-azido-4-chloro-1-nitrobenzene (104503-85-7)

Guidance literature:

With sodium azide; In dimethyl sulfoxide; at 20 ℃; for 1h;

DOI:10.1055/s-0039-1691524

Reference yield:

→ 2-azido-4-chloro-1-nitrobenzene (104503-85-7)

Guidance literature:

5-Chlor-2-nitro-anilin, 1) Diazotierung, 2) Beh. der wss. Diazoniumsalzlsg. mit wss. NaN3;

DOI:10.1039/jr9650005958

upstream raw materials:

5-chloro-2-nitroaniline

4-chloro-2-fluoro-nitrobenzene

Downstream raw materials:

3-(5-chloro-2-nitro-phenyl)-5-p-tolyl-2,3-dihydro-[1,2,3]triazol-4-one

3-(5-chloro-2-nitro-phenyl)-5-phenyl-2,3-dihydro-[1,2,3]triazol-4-one

Refernces

• 1、 Aggarwal, Himanshu,Ewa, Augustynowicz-Kopec,G?ogowska, Agnieszka,Ghosh, Balaram,Kumar, Banoth Karan,Murugesan, Sankaranarayanan,Nandikolla, Adinarayana,Pulya, Sravani,Sekhar, Kondapalli Venkata Gowri Chandra,Srinivasarao, Singireddi,Suresh, Amaroju. "Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agents". . . Retrieved 2020.
• 2、 Bai, Yue-Xia,Li, Long-Ji,Wang, Xiao-Li,Zeng, Cheng-Chu,Hu, Li-Ming. "Design and synthesis of N-hydroxytriazole-4-carboxamides as HIV integrase inhibitors". . p. 423 - 429. Retrieved 2015/06/17.