trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid

Base Information

• Chemical Name: trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid
• CAS No.: 127062-09-3
• Molecular Formula: C₁₀H₁₆O₃
• Molecular Weight: 184.235
• Mol file: 127062-09-3.mol

Synonyms:

Chemical Property of trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid

There total 50 articles about trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(-)-α-pinene (7785-26-4,25766-18-1) → (1'R,3'R)-2-(3'-acetyl-2',2'-dimethylcyclobutyl)acetic acid (473-72-3,17879-35-5,61376-92-9,61826-55-9,64396-97-0,127062-09-3,52305-34-7)

Guidance literature:

With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile; at 20 ℃; for 24h;

DOI:10.1021/jo991773c

Reference yield: 96.0%

3(2),3(2),7-trimethyl-2,5-dioxo-6-oxa-3(1,3)-cyclobutanaoctaphane → (1'R,3'R)-2-(3'-acetyl-2',2'-dimethylcyclobutyl)acetic acid (473-72-3,17879-35-5,61376-92-9,61826-55-9,64396-97-0,127062-09-3,52305-34-7)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 6h;

DOI:10.1007/s11172-019-2575-3

Reference yield: 83.0%

Pinene (80-56-8,177698-18-9,25766-18-1) → (1'R,3'R)-2-(3'-acetyl-2',2'-dimethylcyclobutyl)acetic acid (473-72-3,17879-35-5,61376-92-9,61826-55-9,64396-97-0,127062-09-3,52305-34-7)

Guidance literature:

Pinene; With ozone; In dichloromethane; acetic acid; at 0 ℃;

With semicarbazide hydrochloride; In dichloromethane; acetic acid; at 0 - 20 ℃;

DOI:10.1134/S1070428014080016

upstream raw materials:

(-)-α-pinene

pinocamphone

2-((1R,3R)-3-acetyl-2,2-dimethylcyclobutyl)acetaldehyde

(+)-α-pinene

Downstream raw materials:

((1S)-2.2-dimethyl-3t-acetohydroximoyl-cyclobutyl-(r))-acetic acid

2,2-dimethyl-3-ethylcyclobutaneacetic acid

(+/-)-(3c-amino-2,2-dimethyl-cyclobut-r-yl)-acetic acid

trans-(2,2-dimethyl-3-acetylcyclobutyl)acetic acid