1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE

Base Information

Chemical Name:1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE
CAS No.:104523-09-3
Molecular Formula:C19H18F6N2
Molecular Weight:388.35000
Hs Code.:
Mol file:104523-09-3.mol

Synonyms:1-[Bis-(4-trifluoromethyl-phenyl)-methyl]-piperazine;N-[bis(4-trifluoromethylphenyl)methyl]piperazine;

Suppliers and Price of 1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-{Bis[4-(trifluoromethyl)phenyl]methyl}piperazine
5mg
$ 45.00

American Custom Chemicals Corporation
1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE 95.00%
5MG
$ 496.03

Total 3 raw suppliers

Chemical Property of 1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE

Chemical Property:

PSA：15.27000
LogP:4.98550

Purity/Quality:

99% ^*data from raw suppliers

1-{Bis[4-(trifluoromethyl)phenyl]methyl}piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE

There total 1 articles about 1-(BIS[4-(TRIFLUOROMETHYL)PHENYL]METHYL)PIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 194017-66-8
N-(ethoxycarbonyl)-N'-[bis(4-trifluoromethyl phenyl)methyl]piperazine

: 104523-09-3
4-[4,4'-di(trifluoromethyl)benzhydryl]piperazine

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; ethanol;

Reference yield:

: 194017-71-5
(4-(2-pyridyloxy)phenyl)methyl chloride

: 104523-09-3
4-[4,4'-di(trifluoromethyl)benzhydryl]piperazine

: 194017-56-6
N-[4-(pyrid-2-yloxy)phenylmethyl]-N'-[bis(4-trifluoromethylphenyl)methyl]piperazine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; sodium iodide; In dimethyl sulfoxide;

Reference yield:

: 104523-09-3
4-[4,4'-di(trifluoromethyl)benzhydryl]piperazine

: 1-{4-[Bis-(4-trifluoromethyl-phenyl)-methyl]-piperazin-1-yl}-3-(7H-purin-6-ylsulfanyl)-propan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / ethanol / 18 h / Ambient temperature

2: 12.8 percent / Et₃N / dimethylformamide / 22 h / Ambient temperature

With sodium hydrogencarbonate; triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00102a001