1-cyclopropyl-6-fluoro-8-Methoxy-4-oxo-7-(tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

Base Information

• Chemical Name: 1-cyclopropyl-6-fluoro-8-Methoxy-4-oxo-7-(tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
• CAS No.: 1246654-75-0
• Molecular Formula: C₂₁H₂₄FN₃O₄*ClH
• Molecular Weight: 437.899
• Mol file: 1246654-75-0.mol

Synonyms:

Chemical Property of 1-cyclopropyl-6-fluoro-8-Methoxy-4-oxo-7-(tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

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MSDS Files:

Useful:

Technology Process of 1-cyclopropyl-6-fluoro-8-Methoxy-4-oxo-7-(tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

There total 34 articles about 1-cyclopropyl-6-fluoro-8-Methoxy-4-oxo-7-(tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

(4aS-cis)-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid-O3,O4(bis(acyloxy-O)) borate → moxifloxacin hydrochloride (186826-86-8,1246654-75-0,1346603-25-5)

Guidance literature:

With hydrogenchloride; In methanol; water; at 0 - 8 ℃; for 0.333333h; Temperature;

Reference yield: 92.9%

C27H33BFN3O8 → moxifloxacin hydrochloride (186826-86-8,1246654-75-0,1346603-25-5)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 2h; pH=3; pH-value;

Reference yield: 92.1%

moxifloxacin ethyl ester tartrate → moxifloxacin hydrochloride (186826-86-8,1246654-75-0,1346603-25-5)

Guidance literature:

With hydrogenchloride; In water; at 60 ℃; for 6h; Solvent;

upstream raw materials:

(1S,6S)-2,8-diazabicyclo[4.3.0]nonane

moxifloxacin

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate

1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline-carboxylic acid O₃,O₄-bis(propyloxy-O)borate

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