C₃₂H₃₅F₃N₆O₃

Base Information

Chemical Name:C₃₂H₃₅F₃N₆O₃
CAS No.:1404536-38-4
Molecular Formula:C₃₂H₃₅F₃N₆O₃
Molecular Weight:608.664
Hs Code.:

C<sub>32</sub>H<sub>35</sub>F<sub>3</sub>N<sub>6</sub>O<sub>3</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₃₂H₃₅F₃N₆O₃

Chemical Property:

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Technology Process of C₃₂H₃₅F₃N₆O₃

There total 23 articles about C₃₂H₃₅F₃N₆O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1404532-64-4
{3-[4-(4-butyryl-5-methyl-pyrazol-1-yl)phenylcarbamoyl]-5-methyl-indol-1-yl}acetic acid methyl ester

: 1404536-38-4
C₃₂H₃₅F₃N₆O₃

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / methanol / 20 °C

2: bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / 20 °C / Alkaline conditions

With water; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydroxide; In methanol;
DOI:10.1021/jm500588w

Reference yield:

: 1-acetyl-5-methyl-1H-indole-3-carboxylic acid

: 1404536-38-4
C₃₂H₃₅F₃N₆O₃

Guidance literature:: Multi-step reaction with 5 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C

2: potassium carbonate / methanol / 4 h / 20 °C

3: potassium carbonate / N,N-dimethyl-formamide / 20 °C

4: sodium hydroxide; water / methanol / 20 °C

5: bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / 20 °C / Alkaline conditions

With dmap; water; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm500588w

Reference yield:

: 858515-93-2
2,2,2-trifluoro-1-(5-methyl-1H-indol-3-yl)-ethanone

: 1404536-38-4
C₃₂H₃₅F₃N₆O₃

Guidance literature:: Multi-step reaction with 7 steps

1: potassium hydroxide; water / Reflux

2: dmap; triethylamine / dichloromethane / 0 - 20 °C

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C

4: potassium carbonate / methanol / 4 h / 20 °C

5: potassium carbonate / N,N-dimethyl-formamide / 20 °C

6: sodium hydroxide; water / methanol / 20 °C

7: bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / 20 °C / Alkaline conditions

With dmap; water; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm500588w