2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide

Base Information

Chemical Name:2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide
CAS No.:90513-91-0
Molecular Formula:C₁₇H₂₀ClN₃O₃
Molecular Weight:349.817
Hs Code.:

Synonyms:BRN 0937519;2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide;1H-Pyrrolo(1,2-c)imidazole-5-carboxamide, hexahydro-2-(m-chlorophenyl)-N,N-diethyl-1,3-dioxo-;90513-91-0

Suppliers and Price of 2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:349.1193192
Heavy Atom Count:24
Complexity:537

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1CCC2N1C(=O)N(C2=O)C3=CC(=CC=C3)Cl

Technology Process of 2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide

There total 5 articles about 2-(m-Chlorophenyl)-1,3-dioxohexahydro-1H-pyrrolo(1,2-c)imidazole-5-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41994-50-7
diethyl meso-2,5-pyrrolidinedicarboxylate

: 90513-91-0
2-(3-chloro-phenyl)-1,3-dioxo-hexahydro-pyrrolo[1,2-c]imidazole-5-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / diethyl ether / 1 h / Heating; 1.) room temp., 15 min.

2: 83 percent / 3 h / 235 - 245 °C

3: 69 percent / conc. hydrochloric acid / 1 h / Heating

4: 1.) ethyl chloroformate, triethylamine / 1.) benzene, ether, 0 deg C, 15 min; 2.) benzene, ether, room temp. 20 min

With hydrogenchloride; chloroformic acid ethyl ester; triethylamine; In diethyl ether;

Reference yield:

: 2909-38-8
m-chlorophenyl isocyanate

: 90513-91-0
2-(3-chloro-phenyl)-1,3-dioxo-hexahydro-pyrrolo[1,2-c]imidazole-5-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / diethyl ether / 1 h / Heating; 1.) room temp., 15 min.

2: 83 percent / 3 h / 235 - 245 °C

3: 69 percent / conc. hydrochloric acid / 1 h / Heating

4: 1.) ethyl chloroformate, triethylamine / 1.) benzene, ether, 0 deg C, 15 min; 2.) benzene, ether, room temp. 20 min

With hydrogenchloride; chloroformic acid ethyl ester; triethylamine; In diethyl ether;

Reference yield:

: 90513-60-3
1-(3-Chloro-phenylcarbamoyl)-pyrrolidine-2,5-dicarboxylic acid diethyl ester

: 90513-91-0
2-(3-chloro-phenyl)-1,3-dioxo-hexahydro-pyrrolo[1,2-c]imidazole-5-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / 3 h / 235 - 245 °C

2: 69 percent / conc. hydrochloric acid / 1 h / Heating

3: 1.) ethyl chloroformate, triethylamine / 1.) benzene, ether, 0 deg C, 15 min; 2.) benzene, ether, room temp. 20 min

With hydrogenchloride; chloroformic acid ethyl ester; triethylamine;