C₂₇H₄₂N₂O₈

Base Information

• Chemical Name: C₂₇H₄₂N₂O₈
• CAS No.: 1350745-06-0
• Molecular Formula: C₂₇H₄₂N₂O₈
• Molecular Weight: 522.639
• Mol file: 1350745-06-0.mol

Synonyms:

Chemical Property of C₂₇H₄₂N₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₄₂N₂O₈

There total 5 articles about C₂₇H₄₂N₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

t-Boc-L-valine (13734-41-3) + 6-amine-6-deoxy-1,2-O-isopropylidene-3-C-methyl-3-benzyl-α-glucofuranose (1350745-10-6) → C27H42N2O8 (1350745-06-0)

Guidance literature:

t-Boc-L-valine; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -15 ℃; for 0.75h; Inert atmosphere; Schlenk technique;

6-amine-6-deoxy-1,2-O-isopropylidene-3-C-methyl-3-benzyl-α-glucofuranose; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1002/cctc.201300456

Reference yield:

6-azido-6-deoxy-1,2-O-isopropylidene-3-C-methyl-3-benzyl-α-glucofuranose (1350745-14-0) → C27H42N2O8 (1350745-06-0)

Guidance literature:

Multi-step reaction with 2 steps

1: water; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere

2: tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With water; triphenylphosphine; In tetrahydrofuran;

DOI:10.1039/c1cc15024c

Reference yield:

3-O-benzyl-3-C-methyl-1,2-O-isopropylidene-α-D-glucofuranose (120615-67-0) → C27H42N2O8 (1350745-06-0)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / dichloromethane / 0 °C / Inert atmosphere

2: sodium azide / N,N-dimethyl-formamide / 90 °C / Inert atmosphere

3: water; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere

4: tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With pyridine; sodium azide; water; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c1cc15024c

upstream raw materials:

3-O-benzyl-3-C-methyl-1,2-O-isopropylidene-α-D-glucofuranose

6-azido-6-deoxy-1,2-O-isopropylidene-3-C-methyl-3-benzyl-α-glucofuranose

3-O-benzyl-3-C-methyl-1,2-O-isopropylidene-6-O-tosyl-α-D-glucofuranose

t-Boc-L-valine