(S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester

Base Information

• Chemical Name: (S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester
• CAS No.: 1373396-26-9
• Molecular Formula: C₁₈H₁₆Cl₄N₂O₂
• Molecular Weight: 434.149
• Mol file: 1373396-26-9.mol

Synonyms:

Chemical Property of (S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester

There total 2 articles about (S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester (1373396-04-3) → (R)-3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropan-1-ol (1373396-31-6) + (S)-3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropan-1-ol + (R)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester + (S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester (1373396-26-9)

Guidance literature:

With Candida antarctica lipase B; benzylamine; In acetonitrile; at 20 ℃; for 12.5h; optical yield given as %ee; Enzymatic reaction;

DOI:10.1039/c2ob25247c

Reference yield:

methallyl acetate (820-71-3) → (R)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester + (S)-acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester (1373396-26-9)

Guidance literature:

Multi-step reaction with 2 steps

1: ferrous(II) sulfate heptahydrate / water; dimethyl sulfoxide / 0.25 h / Inert atmosphere

2: Candida antarctica lipase B; benzylamine / acetonitrile / 12.5 h / 20 °C / Enzymatic reaction

With Candida antarctica lipase B; ferrous(II) sulfate heptahydrate; benzylamine; In water; dimethyl sulfoxide; acetonitrile;

DOI:10.1039/c2ob25247c

upstream raw materials:

acetic acid 3-(3,5-dichlorophenyl)-2-(3,5-dichlorophenylazo)-2-methylpropyl ester

methallyl acetate