5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole

Base Information

Chemical Name:5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole
CAS No.:104598-82-5
Molecular Formula:C24H23NO2
Molecular Weight:357.452
Hs Code.:
DSSTox Substance ID:DTXSID001168194
Mol file:104598-82-5.mol

Synonyms:DTXSID001168194;5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole;104598-82-5

Suppliers and Price of 5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole

Chemical Property:

XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:357.172878976
Heavy Atom Count:27
Complexity:455

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N(C2=C1C=C(C=C2)OC)CC3=CC=CC=C3)C4=CC=C(C=C4)OC

Technology Process of 5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole

There total 1 articles about 5-Methoxy-2-(4-methoxyphenyl)-3-methyl-1-(phenylmethyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91444-18-7
5-methoxy-2-(4-methoxyphenyl)-3-methyl-1H-indole

: 100-44-7
benzyl chloride

: 104598-82-5
1-Benzyl-5-methoxy-2-(4-methoxy-phenyl)-3-methyl-1H-indole

Guidance literature:: With sodium hydride; Multistep reaction; 1.) DMF, 0 deg C, 30 min, 2.) DMF, a) 0 deg C, 30 min, b) RT, 4 h;
DOI:10.1021/jm00384a022

Reference yield:

: 104598-82-5
1-Benzyl-5-methoxy-2-(4-methoxy-phenyl)-3-methyl-1H-indole

: 104599-00-0
1-Benzyl-2-(4-hydroxy-phenyl)-3-methyl-1H-indol-5-ol

Guidance literature:: With boron tribromide; In dichloromethane; at -60 - 20 ℃;
DOI:10.1021/jm00384a022

Reference yield:

: 104598-82-5
1-Benzyl-5-methoxy-2-(4-methoxy-phenyl)-3-methyl-1H-indole

: 104599-18-0
Acetic acid 2-(4-acetoxy-phenyl)-1-benzyl-3-methyl-1H-indol-5-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: BBr₃ / CH₂Cl₂ / -60 - 20 °C

2: pyridine / 2 h / Heating

With pyridine; boron tribromide; In dichloromethane;
DOI:10.1021/jm00384a022