(6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol

Base Information

• Chemical Name: (6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol
• CAS No.: 116059-54-2
• Molecular Formula: C₄₆H₇₀O₃S
• Molecular Weight: 703.126
• Mol file: 116059-54-2.mol

Synonyms:

Chemical Property of (6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol

There total 1 articles about (6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl)sulfonyl)benzene (38818-91-6) → (6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol (116059-54-2,116127-28-7)

Guidance literature:

With oxodiperoxymolybdenumpyridine hexamethylphosphoric triamide complex; lithium diisopropyl amide; Yield given. Multistep reaction;

DOI:10.1016/S0040-4039(01)91350-4

Reference yield: 76.5%

acetic anhydride (108-24-7) + (6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol (116059-54-2,116127-28-7) → Acetic acid (3E,7E,11E)-2-benzenesulfonyl-4,8,12,16-tetramethyl-1-((1E,5E,9E)-2,6,10,14-tetramethyl-pentadeca-1,5,9,13-tetraenyl)-heptadeca-3,7,11,15-tetraenyl ester (116059-40-6,116127-30-1)

Guidance literature:

With dmap; In triethylamine; at 20 ℃; for 4h;

DOI:10.1016/S0040-4039(01)91350-4

Reference yield:

(6E,10E,14E,18E,22E,26E)-17-Benzenesulfonyl-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-2,6,10,14,18,22,26,30-octaen-16-ol (116059-54-2,116127-28-7) → phytoene (540-04-5,7699-28-7,13832-76-3,13920-14-4,42482-95-1,115648-62-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 76.5 percent / DMAP / triethylamine / 4 h / 20 °C

2: 84 percent / NaH / tetrahydrofuran / 1 h / 65 °C

3: 80 percent / 2 eq. n-BuMgCl, 2percent Ni(acac)2 / tetrahydrofuran / 2 h / Ambient temperature

With dmap; bis(acetylacetonate)nickel(II); butyl magnesium bromide; sodium hydride; In tetrahydrofuran; triethylamine;

DOI:10.1016/S0040-4039(01)91350-4

upstream raw materials:

(((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl)sulfonyl)benzene

Downstream raw materials:

Acetic acid (3E,7E,11E)-2-benzenesulfonyl-4,8,12,16-tetramethyl-1-((1E,5E,9E)-2,6,10,14-tetramethyl-pentadeca-1,5,9,13-tetraenyl)-heptadeca-3,7,11,15-tetraenyl ester

((6E,10E,14E,16Z,18E,22E,26E)-2,6,10,14,19,23,27,31-Octamethyl-dotriaconta-2,6,10,14,16,18,22,26,30-nonaene-16-sulfonyl)-benzene

phytoene