all-trans-9,10-Didehydro-19-norretinal

Base Information

• Chemical Name: all-trans-9,10-Didehydro-19-norretinal
• CAS No.: 101315-18-8
• Molecular Formula: C₁₉H₂₄O
• Molecular Weight: 268.399
• Mol file: 101315-18-8.mol

Synonyms:

Chemical Property of all-trans-9,10-Didehydro-19-norretinal

Chemical Property:

Purity/Quality:

99% ，98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of all-trans-9,10-Didehydro-19-norretinal

There total 3 articles about all-trans-9,10-Didehydro-19-norretinal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-5-(2,6,6-trimethylcyclohex-1-enyl)pent-4-en-2-yn-1-ol (101315-21-3) → all-trans-9,10-Didehydro-19-norretinal (101315-18-8)

Guidance literature:

Multi-step reaction with 3 steps

1: MnO₂ / diethyl ether / 17 h

2: 1) NaH / 1) THF, 1 h; 2) ether, 3 h, RT

3: 1) DIBAH; 2.) 1 N HCl / 1.) hexane, 3 h, room temperature; 2.) CH₃OH

With hydrogenchloride; manganese(IV) oxide; sodium hydride; diisobutylaluminium hydride; In diethyl ether;

DOI:10.1002/jlac.198619860811

Reference yield:

(E)-2-(but-1-en-3-ynyl)-1,3,3-trimethylcyclohex-1-ene (73395-75-2) → all-trans-9,10-Didehydro-19-norretinal (101315-18-8)

Guidance literature:

Multi-step reaction with 4 steps

2: MnO₂ / diethyl ether / 17 h

3: 1) NaH / 1) THF, 1 h; 2) ether, 3 h, RT

4: 1) DIBAH; 2.) 1 N HCl / 1.) hexane, 3 h, room temperature; 2.) CH₃OH

With hydrogenchloride; manganese(IV) oxide; sodium hydride; diisobutylaluminium hydride; In diethyl ether;

DOI:10.1002/jlac.198619860811

Reference yield:

5-(2',6',6'-trimethyl-1'-cyclohexen-1'-yl)-4-penten-2-yn-1-al (101315-22-4) → all-trans-9,10-Didehydro-19-norretinal (101315-18-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) NaH / 1) THF, 1 h; 2) ether, 3 h, RT

2: 1) DIBAH; 2.) 1 N HCl / 1.) hexane, 3 h, room temperature; 2.) CH₃OH

With hydrogenchloride; sodium hydride; diisobutylaluminium hydride;

DOI:10.1002/jlac.198619860811

upstream raw materials:

5-(2',6',6'-trimethyl-1'-cyclohexen-1'-yl)-4-penten-2-yn-1-al

(E)-5-(2,6,6-trimethylcyclohex-1-enyl)pent-4-en-2-yn-1-ol

(E)-2-(but-1-en-3-ynyl)-1,3,3-trimethylcyclohex-1-ene

Refernces