Spiro[3.4]octan-5-one

Base Information

• Chemical Name: Spiro[3.4]octan-5-one
• CAS No.: 10468-36-7
• Molecular Formula: C8H12O
• Molecular Weight: 124.18000
• Mol file: 10468-36-7.mol

Synonyms:Spiro[3.4]octan-5-on;spiro[3.4]octan-5-one;Spiro<3.4>octan-1-on;Spiro<3.4>octan-5-on;Spiro<3.4>octanon-(5);Spiro<3,4>octan-5-on;

Chemical Property of Spiro[3.4]octan-5-one

Chemical Property:

• Boiling Point: 57 °C (10 mmHg)
• PSA: 17.07000
• LogP: 1.90970

Purity/Quality:

97% ^*data from raw suppliers

Spiro[3.4]octan-5-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Spiro[3.4]octan-5-one

There total 8 articles about Spiro[3.4]octan-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

1'-Phenylsulfanyl-bicyclobutyl-1-ol → Spiro<3.4>octan-5-on (10468-36-7)

Guidance literature:

With tin(IV) chloride; In dichloromethane; 0 deg C, 15 min; RT, 5 min;

DOI:10.1016/00404-0399(50)0958F-

Reference yield:

bicyclobutyl-1,1'-diol (82491-67-6) → Spiro<3.4>octan-5-on (10468-36-7)

Guidance literature:

With sulfuric acid; water;

Reference yield:

9-oxa-dispiro[3.0.3.1]nonane (37677-06-8) → Spiro<3.4>octan-5-on (10468-36-7)

Guidance literature:

at 200 ℃;

DOI:10.1021/jo00903a017

upstream raw materials:

2-(3'-bromopropyl)cyclopentanone

bicyclobutyl-1,1'-diol

9-oxa-dispiro[3.0.3.1]nonane

1,1'-bi(cyclobutylidene)

Downstream raw materials:

Spiro<3.4>oct-5-en

6,6-dimethyl-spiro[3.4]octan-5-one

(+/-)-(5R,6R)-5,6-dimethyl-spiro[3.4]octan-5-ol

(+/-)-(5R,6S)-5,6-dimethyl-spiro[3.4]octan-5-ol