Technology Process of (-)-(3'S,4'S)-5-<3',4'-Bis<(trimethylsilyl)oxy>-2',6',6'-trimethylcyclohex-1'-enyl>-3-methylpenta-2,4-dienal
There total 8 articles about (-)-(3'S,4'S)-5-<3',4'-Bis<(trimethylsilyl)oxy>-2',6',6'-trimethylcyclohex-1'-enyl>-3-methylpenta-2,4-dienal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 3.94 g / 9-BBN / tetrahydrofuran / 0 °C
2: 88 percent / pyridine
3: 4.20 g / conc. H2SO4 / acetic acid / 0.25 h
4: 31 percent / K2CO3 / methanol; H2O / Ambient temperature
5: 98 percent / hexamethyl disilazane / pyridine / Ambient temperature
6: 1.50 g / DIBAH / hexane; diethyl ether / -10 °C
With
pyridine; 9-borabicyclo[3.3.1]nonane dimer; diisobutylaluminium hydride; potassium carbonate; 1,1,1,3,3,3-hexamethyl-disilazane;
sulfuric acid;
In
tetrahydrofuran; pyridine; methanol; diethyl ether; hexane; water; acetic acid;
DOI:10.1002/hlca.19900730426
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 7.54 g / TsOH*H2O / acetone / 25 h / Ambient temperature
2: 3.94 g / 9-BBN / tetrahydrofuran / 0 °C
3: 88 percent / pyridine
4: 4.20 g / conc. H2SO4 / acetic acid / 0.25 h
5: 31 percent / K2CO3 / methanol; H2O / Ambient temperature
6: 98 percent / hexamethyl disilazane / pyridine / Ambient temperature
7: 1.50 g / DIBAH / hexane; diethyl ether / -10 °C
With
pyridine; 9-borabicyclo[3.3.1]nonane dimer; diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; 1,1,1,3,3,3-hexamethyl-disilazane;
sulfuric acid;
In
tetrahydrofuran; pyridine; methanol; diethyl ether; hexane; water; acetic acid; acetone;
DOI:10.1002/hlca.19900730426