2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester

Base Information

Chemical Name:2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester
CAS No.:104801-82-3
Molecular Formula:C23H44O4
Molecular Weight:384.6
Hs Code.:
Mol file:104801-82-3.mol

Synonyms:.7-carbomethoxy-8-oxo-10-hydroxyheneicosane;2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester;methyl 2-hexyl-5-hydroxy-3-oxohexadecanoate;

Suppliers and Price of 2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hexyl-5-hydroxy-3-oxo-hexadecanoicAcidMethylEster
500mg
$ 1320.00

Medical Isotopes, Inc.
2-Hexyl-5-hydroxy-3-oxo-hexadecanoicAcidMethylEster
500 mg
$ 2200.00

Medical Isotopes, Inc.
2-Hexyl-5-hydroxy-3-oxo-hexadecanoicAcidMethylEster
50 mg
$ 650.00

American Custom Chemicals Corporation
2-HEXYL-5-HYDROXY-3-OXO-HEXADECANOIC ACID METHYL ESTER 95.00%
5MG
$ 501.50

Total 3 raw suppliers

Chemical Property of 2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester

Chemical Property:

Melting Point:34 °C
Boiling Point:478.9±20.0 °C(Predicted)
PKA:11.62±0.59(Predicted)
PSA：63.60000
Density:0.944±0.06 g/cm3(Predicted)
LogP:5.98700
Solubility.:Chloroform, Ethyl Acetate, Tetrahydrofuran

Purity/Quality:

99% ^*data from raw suppliers

2-Hexyl-5-hydroxy-3-oxo-hexadecanoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester is a reactant used in the preparation of oxetanone derivatives as lipase inhibitors and potential anti-obesity compounds such as tetrahydrolipstatin.

Technology Process of 2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester

There total 10 articles about 2-Hexyl-5-hydroxy-3-oxo-hexadecanoic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 252727-28-9
7-carbomethoxy-8-oxo-10-tert-butyldimethylsilyloxyheneicosane

: 104801-82-3
methyl 2-hexyl-5-hydroxy-3-oxo-hexadecanoate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at -78 ℃; for 6h;
DOI:10.1021/jo990370+

Reference yield: 48.0%

: 70203-04-2
2-acetyl-octanoic acid methyl ester

: 112-54-9
Dodecanal

: 104801-82-3
methyl 2-hexyl-5-hydroxy-3-oxo-hexadecanoate

Guidance literature:: With n-butyllithium; sodium hydride; In tetrahydrofuran; hexane; 1.) 1 h, room t.; 2.) 0 degC, 15 min, room t., 1 h;
DOI:10.1002/hlca.19870700124

Reference yield:

: 112-54-9
Dodecanal

: 104801-82-3
methyl 2-hexyl-5-hydroxy-3-oxo-hexadecanoate

Guidance literature:: Multi-step reaction with 6 steps

1.1: 92 percent / Zn; NH₄Cl / tetrahydrofuran; H₂O / 1 h

2.1: 86 percent / NaH / tetrahydrofuran / 12 h / 20 °C

3.1: ozone / CH₂Cl₂ / 2 h

3.2: 81 percent / triphenylphosphine / CH₂Cl₂ / 40 h / 0 °C

4.1: 45 percent / Zn / benzene / 2 h / ultrasound

5.1: 72 percent / pyridinium chlorochromate; NaOAc / CH₂Cl₂ / 0 °C

6.1: 68 percent / TBAF / tetrahydrofuran / 6 h / -78 °C

With tetrabutyl ammonium fluoride; sodium acetate; sodium hydride; ammonium chloride; ozone; pyridinium chlorochromate; zinc; In tetrahydrofuran; dichloromethane; water; benzene; 1.1: Alkylation / 2.1: silylation / 3.1: ozonolysis / 3.2: Reduction / 4.1: Reformatsky reaction / 5.1: Oxidation / 6.1: desilylation;
DOI:10.1021/jo990370+