C₁₉H₁₃ClN₆

Base Information

• Chemical Name: C₁₉H₁₃ClN₆
• CAS No.: 1255926-92-1
• Molecular Formula: C₁₉H₁₃ClN₆
• Molecular Weight: 360.805
• Mol file: 1255926-92-1.mol

Synonyms:

Chemical Property of C₁₉H₁₃ClN₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₁₃ClN₆

There total 10 articles about C₁₉H₁₃ClN₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 4-chloropyrrolo[1,2-a]quinoxaline-6-carboxylate (1255927-18-4) → C19H13ClN6 (1255926-92-1)

Guidance literature:

Multi-step reaction with 6 steps

1: water; sodium hydroxide / ethanol / 80 °C

2: ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 80 °C

3: 80 °C / Neat (no solvent)

4: hydrazine hydrate / acetic acid / 80 °C

5: triethylamine; trichlorophosphate / acetonitrile / 100 °C

6: 1-methyl-pyrrolidin-2-one / 120 - 140 °C / Microwave irradiation

With water; ammonium chloride; benzotriazol-1-ol; hydrazine hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; trichlorophosphate; In 1,4-dioxane; 1-methyl-pyrrolidin-2-one; ethanol; acetic acid; acetonitrile;

DOI:10.1016/j.bmcl.2012.02.099

Reference yield:

C15H14N4O2 → C19H13ClN6 (1255926-92-1)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / acetic acid / 80 °C

2: triethylamine; trichlorophosphate / acetonitrile / 100 °C

3: 1-methyl-pyrrolidin-2-one / 120 - 140 °C / Microwave irradiation

With hydrazine hydrate; triethylamine; trichlorophosphate; In 1-methyl-pyrrolidin-2-one; acetic acid; acetonitrile;

DOI:10.1016/j.bmcl.2012.02.099

Reference yield:

C13H9N5O (1255927-23-1) → C19H13ClN6 (1255926-92-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; trichlorophosphate / acetonitrile / 100 °C

2: 1-methyl-pyrrolidin-2-one / 120 - 140 °C / Microwave irradiation

With triethylamine; trichlorophosphate; In 1-methyl-pyrrolidin-2-one; acetonitrile;

DOI:10.1016/j.bmcl.2012.02.099

upstream raw materials:

ethyl 2-nitro-3-(1H-pyrrol-1-yl)benzoate

ethyl 2-amino-3-(1H-pyrrol-1-yl)benzoate

ethyl 4-chloropyrrolo[1,2-a]quinoxaline-6-carboxylate

C₁₂H₈N₂O₃