Technology Process of 11,12-di(biphenyl-2-yl)-11,12-dihydroindeno[2,1-a]fluorene-11,12-diol
There total 4 articles about 11,12-di(biphenyl-2-yl)-11,12-dihydroindeno[2,1-a]fluorene-11,12-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-Bromobiphenyl;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.9h;
Inert atmosphere;
indeno[2,1-a]fluorene-11,12-dione;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1002/chem.201001830
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: water; sodium hydroxide / ethanol / 16 h / 90 °C
2.1: sulfuric acid / 0.08 h / 140 °C
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.9 h / -78 °C / Inert atmosphere
3.2: -78 - 20 °C / Inert atmosphere
With
n-butyllithium; sulfuric acid; water; sodium hydroxide;
In
tetrahydrofuran; ethanol; hexane;
DOI:10.1002/chem.201001830
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: chromium(VI) oxide; acetic anhydride / 20 h / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.9 h / -78 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
With
chromium(VI) oxide; n-butyllithium; acetic anhydride;
In
tetrahydrofuran; hexane;
DOI:10.1002/chem.201001830
