Technology Process of Di-Z-His-Leu-Met-NH2
There total 1 articles about Di-Z-His-Leu-Met-NH2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diphenyl-phosphinic acid; triethylamine;
Yield given;
1.) DMF, 0 deg C, 20 min, 2.) DMF, a) 0 deg C, 3 h, b) RT, 72 h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: HBr / acetic acid / 1 h / Ambient temperature
2: 37 percent / triethylamine / dimethylformamide / 240 h / Ambient temperature
3: 87 percent / 4.2M HCl / dioxane / 0.5 h / Ambient temperature
4: 54 percent / triethylamine / dimethylformamide / 240 h / Ambient temperature
With
hydrogenchloride; hydrogen bromide; triethylamine;
In
1,4-dioxane; acetic acid; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: HBr / acetic acid / 1 h / Ambient temperature
2: 37 percent / triethylamine / dimethylformamide / 240 h / Ambient temperature
3: 87 percent / 4.2M HCl / dioxane / 0.5 h / Ambient temperature
4: 54 percent / triethylamine / dimethylformamide / 240 h / Ambient temperature
5: 90 percent / 4.2M HCl / dioxane / 0.5 h / Ambient temperature
6: 39 percent / triethylamine, dicyclohexylcarbodiimide / dimethylformamide / 24 h
With
hydrogenchloride; hydrogen bromide; triethylamine; dicyclohexyl-carbodiimide;
In
1,4-dioxane; acetic acid; N,N-dimethyl-formamide;
