(R)-Pronuciferine

Base Information

• Chemical Name: (R)-Pronuciferine
• CAS No.: 17236-29-2
• Molecular Formula: C₁₉H₂₁NO₃
• Molecular Weight: 311.381
• DSSTox Substance ID: DTXSID201106774
• Nikkaji Number: J2.288.910I
• Wikidata: Q105313394
• Mol file: 17236-29-2.mol

Synonyms:[8'aR,(+)]-2',3',8',8'a-Tetrahydro-5',6'-dimethoxy-1'-methylspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one;(R)-Pronuciferine;ChemDiv2_002092;SCHEMBL2684479;DTXSID201106774;HMS1374P02;AKOS000732402;AKOS022011456;CCG-119547;17236-29-2;2',3',8',8'a-Tetrahydro-5',6'-dimethoxy-1'-methylspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one;5',6'-dimethoxy-1'-methyl-2',3',8',8a'-tetrahydro-1'H,4H-spiro[cyclohexa-2,5-diene-1,7'-cyclopenta[ij]isoquinolin]-4-one

Chemical Property of (R)-Pronuciferine

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 311.15214353
• Heavy Atom Count: 23
• Complexity: 539

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1CCC2=CC(=C(C3=C2C1CC34C=CC(=O)C=C4)OC)OC

Technology Process of (R)-Pronuciferine

There total 1 articles about (R)-Pronuciferine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

1-(4-Azido-benzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline → pronuciferine (17236-29-2) + 4-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-aniline (55968-69-9)

Guidance literature:

With trifluorormethanesulfonic acid; In trifluoroacetic acid; at 0 - 5 ℃;

DOI:10.1039/C39890000003