trans-chrysanthenol

Base Information

• Chemical Name: trans-chrysanthenol
• CAS No.: 19890-11-0
• Molecular Formula: C₁₀H₁₆O
• Molecular Weight: 152.236
• Mol file: 19890-11-0.mol

Synonyms:

Chemical Property of trans-chrysanthenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-chrysanthenol

There total 4 articles about trans-chrysanthenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

7,7-dimethyl-2-methylenebicyclo<3.1.1>heptan-6-one (107514-23-8) → trans-chrysanthenol (19890-11-0,33644-17-6,38043-83-3,55722-60-6,74033-48-0,80581-42-6,111957-76-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 25 ℃;

DOI:10.1021/jo00384a035

Reference yield:

(E)-geranic acid (4698-08-2) → trans-chrysanthenol (19890-11-0,33644-17-6,38043-83-3,55722-60-6,74033-48-0,80581-42-6,111957-76-7)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl chloride / benzene / a) 25 deg C, 2 h, b) 45 deg C, 30 min

2: 43 percent / Et₃N / toluene / 3 h / Heating

3: 67 percent / LAH / tetrahydrofuran / 25 °C

With lithium aluminium tetrahydride; oxalyl dichloride; triethylamine; In tetrahydrofuran; toluene; benzene;

DOI:10.1021/jo00384a035

Reference yield:

(2E)-3,7-dimethyl-2,6-octadienoyl chloride (58558-13-7) → trans-chrysanthenol (19890-11-0,33644-17-6,38043-83-3,55722-60-6,74033-48-0,80581-42-6,111957-76-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 43 percent / Et₃N / toluene / 3 h / Heating

2: 67 percent / LAH / tetrahydrofuran / 25 °C

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; toluene;

DOI:10.1021/jo00384a035

upstream raw materials:

chrysanthenone

7,7-dimethyl-2-methylenebicyclo<3.1.1>heptan-6-one

(E)-geranic acid

(2E)-3,7-dimethyl-2,6-octadienoyl chloride

Downstream raw materials:

3,7-dimethyl-3,6-octadienal

Pseudocyclocitral

2,2,4-trimethyl-cyclohex-3-enecarbaldehyde

1,8-menthadien-5-ol