bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid

Base Information

• Chemical Name: bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid
• CAS No.: 28871-80-9
• Molecular Formula: C10H12 O4
• Molecular Weight: 196.203
• Hs Code.: 2917209090
• Mol file: 28871-80-9.mol

Synonyms:Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylicacid, (1a,2a,3b,4a)-;Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid, trans- (8CI);Bicyclo[2.2.2]oct-2-ene-5,6-trans-dicarboxylic acid; NSC 238002

Chemical Property of bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid

Chemical Property:

• Vapor Pressure: 2.2E-08mmHg at 25°C
• Boiling Point: 424.2°C at 760 mmHg
• Flash Point: 224.5°C
• PSA: 74.60000
• Density: 1.394g/cm³
• LogP: 0.98400

Purity/Quality:

98%min ^*data from raw suppliers

Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid

There total 7 articles about bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fumaryl dichloride (627-63-4) + cyclohexa-1,3-diene (1165952-91-9) → bicyclo<2.2.2>oct-5-ene 2,3-endo,exo-dicarboxylic acid (28871-80-9)

Guidance literature:

anschliessend mit wss. NaOH behandeln;

DOI:10.1139/v59-209

Reference yield:

bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride (6708-37-8,85081-13-6,85081-14-7) → bicyclo<2.2.2>oct-5-ene 2,3-endo,exo-dicarboxylic acid (28871-80-9)

Guidance literature:

Multistep reaction; (i) NaOMe, MeOH, (ii) aq. HCl;

DOI:10.1021/ja00853a036

Reference yield:

→ bicyclo<2.2.2>oct-5-ene 2,3-endo,exo-dicarboxylic acid (28871-80-9)

Guidance literature:

With acetic acid; zinc;

upstream raw materials:

fumaryl dichloride

cyclohexa-1,3-diene

bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride

trans-Bicyclo<2.2.2>octen-(5)-2,3-dicarboxychlorid

Downstream raw materials:

bicyclo[2.2.2]octa-2,5-diene

(+/-)-cyclohexane-1r,2c,3t,4t-tetracarboxylic acid

cis-endo-bicyclo<2.2.2>oct-5-ene-2,3-dicarboxylic acid anhydride

meso-endo-tetrahydro-4,7-ethanoisobenzofuran-1,3-dione