(S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Base Information

Chemical Name:(S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate
CAS No.:1442044-28-1
Molecular Formula:C₃₇H₄₆N₄O₈
Molecular Weight:674.794
Hs Code.:

(S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Synonyms:

Suppliers and Price of (S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

There total 5 articles about (S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1072440-16-4
(2R)-methyl 4-((3S,4R,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-hydroxytetrahydro-2H-pyran-2-yl)-2-(tert-butoxycarbonylamino)butanoate

: 1442044-28-1
(S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Guidance literature:: Multi-step reaction with 3 steps

1: Dess-Martin periodane / dichloromethane / 12 h / 20 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 1 h / -10 °C / Inert atmosphere

3: diphenyl phosphoryl azide; diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran / 26 h / Inert atmosphere

With sodium tetrahydroborate; diphenyl phosphoryl azide; Dess-Martin periodane; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo401044x

Reference yield:

: 1072440-22-2
(2S,6S,7R,8R,9R,Z)-methyl 7,8,10-tris(benzyloxy)-2-(tert-butoxycarbonylamino)-6,9-dihydroxydec-4-enoate

: 1442044-28-1
(S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Guidance literature:: Multi-step reaction with 4 steps

1: mercury(II) trifluoroacetate

2: Dess-Martin periodane / dichloromethane / 12 h / 20 °C / Inert atmosphere

3: sodium tetrahydroborate / methanol / 1 h / -10 °C / Inert atmosphere

4: diphenyl phosphoryl azide; diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran / 26 h / Inert atmosphere

With sodium tetrahydroborate; diphenyl phosphoryl azide; mercury(II) trifluoroacetate; Dess-Martin periodane; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo401044x

Reference yield:

: 93125-77-0
(2R,3R,4R,5S)-1,3,4-tris(benzyloxy)hept-6-ene-2,5-diol

: 1442044-28-1
(S)-methyl 4-((2S,3S,4R,5S,6R)-3-azido-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2yl)-2-((tert-butoxycarbonyl)amino)butanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane

2: mercury(II) trifluoroacetate

3: Dess-Martin periodane / dichloromethane / 12 h / 20 °C / Inert atmosphere

4: sodium tetrahydroborate / methanol / 1 h / -10 °C / Inert atmosphere

5: diphenyl phosphoryl azide; diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran / 26 h / Inert atmosphere

With dmap; sodium tetrahydroborate; diphenyl phosphoryl azide; mercury(II) trifluoroacetate; Dess-Martin periodane; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo401044x