Technology Process of C12H16Cl3NO
There total 5 articles about C12H16Cl3NO which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(R)-Perillyl alcohol; trichloroacetonitrile;
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
at 20 ℃;
In
toluene;
at 110 ℃;
DOI:10.1016/j.tetlet.2014.01.039
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C
2.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C
3.1: pyridine / dichloromethane / 0 - 20 °C
4.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 15 h / 110 °C / Inert atmosphere; Sealed tube
4.2: 20 °C
5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 °C
5.2: 110 °C
With
pyridine; tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane;
5.1: |Overman Rearrangement / 5.2: |Overman Rearrangement;
DOI:10.1016/j.tetlet.2014.01.039
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C
2.1: pyridine / dichloromethane / 0 - 20 °C
3.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 15 h / 110 °C / Inert atmosphere; Sealed tube
3.2: 20 °C
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 °C
4.2: 110 °C
With
pyridine; tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane;
4.1: |Overman Rearrangement / 4.2: |Overman Rearrangement;
DOI:10.1016/j.tetlet.2014.01.039
