C₁₅H₁₂N₂

Base Information

• Chemical Name: C₁₅H₁₂N₂
• CAS No.: 1273927-77-7
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.274
• Mol file: 1273927-77-7.mol

Synonyms:

Chemical Property of C₁₅H₁₂N₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₅H₁₂N₂

There total 1 articles about C₁₅H₁₂N₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoindoline (496-12-8) + 2-fluorobenzonitrile (394-47-8) → C15H12N2 (1273927-77-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 12h;

DOI:10.1002/adsc.201300455

Reference yield:

C15H12N2 (1273927-77-7) → 2-(isoindolin-2-yl)benzamide

Guidance literature:

C₁₅H₁₂N₂; With sulfuric acid; acetic acid; at 120 ℃; for 2h;

With water; Cooling with ice;

DOI:10.1002/adsc.201300455

Reference yield:

C15H12N2 (1273927-77-7) → isoindolo[2,1-a]quinazolin-5-(11H)-one (26963-23-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic acid; sulfuric acid / 2 h / 120 °C

1.2: Cooling with ice

2.1: bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; 2-hydroxypyridin / 2,2,2-trifluoroethanol / 12 h / 100 °C / Inert atmosphere

With 2-hydroxypyridin; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sulfuric acid; acetic acid; In 2,2,2-trifluoroethanol;

DOI:10.1002/adsc.201300455

upstream raw materials:

isoindoline

2-fluorobenzonitrile

Downstream raw materials:

isoindolo[2,1-a]quinazolin-5-(11H)-one