Chemical Property of C10H23N4(CH2C6H4CH2OH)
Chemical Property:
- Boiling Point:496.9±45.0 °C(Predicted)
- Density:1.002±0.06 g/cm3(Predicted)
- Purity/Quality:
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> 95% *data from raw suppliers
N-(4-Hydroxymethylbenzyl)Cyclam *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
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Uses
N-(4-Hydroxymethylbenzyl) Cyclam is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin''s lymphoma (NHL) and multiple myeloma (MM).
