Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol

Base Information

• Chemical Name: Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol
• CAS No.: 82416-28-2
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.252
• Mol file: 82416-28-2.mol

Synonyms:

Chemical Property of Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol

There total 1 articles about Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2,4-dimethylcyclohexan-1-ol (23713-65-7,59338-76-0,59338-77-1,59338-78-2,82416-23-7,82416-24-8,82416-25-9,82416-26-0,82416-31-7,82416-32-8,111003-03-3,111003-05-5,113776-10-6,69542-91-2) + acetic anhydride (108-24-7) → Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol (82416-28-2,82416-29-3,82416-30-6,110911-31-4,111003-04-4)

Guidance literature:

In pyridine; at 20 ℃; for 20h;

Reference yield:

Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol (82416-28-2,82416-29-3,82416-30-6,110911-31-4,111003-04-4) → (+)-(2S,4R)-trans-2,4-dimethyl-1-cyclohexanone (93921-42-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Bacillus subtilis var. niger IFO 3108, 2.) LiAlH₄ / 1.) 27 deg C, 2 d, 2.) ether, 20 deg C, 1.5 h

2: 88 percent / pyridinium chlorochromate, sodium acetate / CH₂Cl₂ / 1.5 h / 20 °C

With lithium aluminium tetrahydride; Bacillus subtilis var. niger IFO 3108; sodium acetate; pyridinium chlorochromate; In dichloromethane;

Reference yield:

Acetate of (+/-)-2,4-Dimethyl-1-cyclohexanol (82416-28-2,82416-29-3,82416-30-6,110911-31-4,111003-04-4) → c-2,t-4-Dimethyl-r-1-cyclohexanol (111003-03-3)

Guidance literature:

With Bacillus subtilis var. niger IFO 3108; at 27 ℃; for 48h;

upstream raw materials:

2,4-dimethylcyclohexan-1-ol

acetic anhydride

Downstream raw materials:

(-)-(1S,2R,4S)-2,4-dimethylcyclohexanol

c-2,t-4-Dimethyl-r-1-cyclohexanol

(+)-(2S,4R)-trans-2,4-dimethyl-1-cyclohexanone

Refernces