Technology Process of C23H30BrFN4O3
There total 6 articles about C23H30BrFN4O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bromine; acetic acid;
In
dichloromethane;
at 20 ℃;
for 0.5h;
DOI:10.1021/jm300041e
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / dichloromethane / 3 h / 20 °C
2: sodium azide / N,N-dimethyl-formamide / 20 °C
3: palladium on activated charcoal; hydrogen / methanol / 20 °C
4: sodium hydroxide / tetrahydrofuran / 24 h / 20 - 40 °C
5: bromine; acetic acid / dichloromethane / 0.5 h / 20 °C
With
sodium azide; palladium on activated charcoal; hydrogen; bromine; acetic acid; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm300041e
- Guidance literature:
-
Multi-step reaction with 7 steps
1: palladium on activated charcoal; hydrogen / methanol / 72 h / 25 °C
2: borane-THF / tetrahydrofuran / Reflux
3: triethylamine / dichloromethane / 3 h / 20 °C
4: sodium azide / N,N-dimethyl-formamide / 20 °C
5: palladium on activated charcoal; hydrogen / methanol / 20 °C
6: sodium hydroxide / tetrahydrofuran / 24 h / 20 - 40 °C
7: bromine; acetic acid / dichloromethane / 0.5 h / 20 °C
With
sodium azide; borane-THF; palladium on activated charcoal; hydrogen; bromine; acetic acid; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm300041e
