Technology Process of C30H35N3O6S
There total 8 articles about C30H35N3O6S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C27H29N3O6S; isopropenylmagnesium bromide;
In
tetrahydrofuran;
at -78 - 0 ℃;
Inert atmosphere;
With
hydrogenchloride; water;
In
tetrahydrofuran;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1021/ol2020362
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diisopropyl-carbodiimide / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere
2.1: lithium hexamethyldisilazane / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -78 °C / Inert atmosphere
2.2: -78 °C / Inert atmosphere
2.3: -78 - 20 °C / Inert atmosphere
3.1: methanol; thionyl chloride / 2 h / 0 - 20 °C / Inert atmosphere
3.2: 120 °C / Inert atmosphere
3.3: 48 h / 20 °C / Inert atmosphere
4.1: tetrahydrofuran / -78 - 0 °C / Inert atmosphere
4.2: Inert atmosphere
With
methanol; thionyl chloride; lithium hexamethyldisilazane; diisopropyl-carbodiimide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
DOI:10.1021/ol2020362
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -78 °C / Inert atmosphere
1.2: -78 °C / Inert atmosphere
1.3: -78 - 20 °C / Inert atmosphere
2.1: methanol; thionyl chloride / 2 h / 0 - 20 °C / Inert atmosphere
2.2: 120 °C / Inert atmosphere
2.3: 48 h / 20 °C / Inert atmosphere
3.1: tetrahydrofuran / -78 - 0 °C / Inert atmosphere
3.2: Inert atmosphere
With
methanol; thionyl chloride; lithium hexamethyldisilazane;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
DOI:10.1021/ol2020362
