benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate

Base Information

• Chemical Name: benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate
• CAS No.: 1309440-34-3
• Molecular Formula: C₃₂H₃₁BrN₂O₅
• Molecular Weight: 603.513
• Mol file: 1309440-34-3.mol

Synonyms:

Chemical Property of benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate

There total 1 articles about benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-benzyl carbamate (621-84-1) + [1-(3-Bromo-phenyl)-meth-(E)-ylidene]-(4-methoxy-phenyl)-amine (28168-89-0) + methyl (4-methylphenyl)diazoacetate (73764-13-3) → benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate (1309440-34-3) + benzyl 1-(methoxycarbonyl)-2-(4-methoxyphenylamino)-2-(3-bromophenyl)-1-p-tolylethylcarbamate

Guidance literature:

With (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate; rhodium(II) acetate dimer; L-Tartaric acid; In toluene; at -20 ℃; for 8h; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Molecular sieve;

DOI:10.1021/ja201589k

upstream raw materials:

O-benzyl carbamate

[1-(3-Bromo-phenyl)-meth-(E)-ylidene]-(4-methoxy-phenyl)-amine

methyl (4-methylphenyl)diazoacetate