Technology Process of C28H20FN6P
There total 4 articles about C28H20FN6P which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hexachloroethane; triethylamine / toluene / 80 °C
2: caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium diacetate / toluene / 16 h / 100 °C / Inert atmosphere
3: 5% Pd/C; hydrogen / ethyl acetate; methanol / 16 h / 20 °C / 3040.2 Torr
4: acetic acid / 0 - 20 °C
With
hexachloroethane; 5% Pd/C; hydrogen; palladium diacetate; caesium carbonate; acetic acid; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
methanol; ethyl acetate; toluene;
1: |Buchwald-Hartwig Coupling;
DOI:10.1016/j.tetlet.2012.07.106
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 5% Pd/C; hydrogen / ethyl acetate; methanol / 16 h / 20 °C / 3040.2 Torr
2: acetic acid / 0 - 20 °C
With
5% Pd/C; hydrogen; acetic acid;
In
methanol; ethyl acetate;
DOI:10.1016/j.tetlet.2012.07.106
- Guidance literature:
-
Multi-step reaction with 3 steps
1: caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; palladium diacetate / toluene / 16 h / 100 °C / Inert atmosphere
2: 5% Pd/C; hydrogen / ethyl acetate; methanol / 16 h / 20 °C / 3040.2 Torr
3: acetic acid / 0 - 20 °C
With
5% Pd/C; hydrogen; palladium diacetate; caesium carbonate; acetic acid; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
methanol; ethyl acetate; toluene;
DOI:10.1016/j.tetlet.2012.07.106
